Uses of CBD in Medicine | Bitneni

CBD in Medicine

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Throughout history, many civilizations have used cannabis as a treatment for different diseases because of its natural curative properties.

Only now are we rediscovering CBD’s medicinal uses. It has already been legalized for medical uses in several countries such as Canada, Italy and some of the United States.

How does it work?

Our body has its own system to recognise Cannabis: the endocannabinoid system. Its main function is to allow our body process cannabis, and metabolise it.

It works through two receptors, called CB1 and CB2. They work together, receiving cannabis and sending signals to the brain, so several processes can start.

Regenerate Magazine

EVIDENCE OF CBD ON SEVERAL DISEASES:

As mentioned before, CBD has been used throughout history to treat many diseases. Today’s medical system enables us to do much deeper research about drugs, and their relationships with diseases.

The following is a list of diseases which CBD pose a potential cure or alleviating element for:

EPILEPSY

The usage of CBD in epilepsy has been studied for decades. In 2018 Epidiolex, the first CBD-medical treatment for epilepsy, was approved by the FDA to treat two types of epilepsy:

  • Lennox-Gastaut Syndrome
  • Dravet syndrome (also known as Myoclonic Epilepsy of Infancy or MIEI)

There is significant research backing up CBD as a possible treatment for epilepsy, particularly those that are hard to treat with conventional medication, or strains that quickly gain drug resistance over time.

The studies conclude that CBD may reduce seizures, from an average of 50% to 100% (most of the studies were done using Epidiolex). This was especially prevalent in children, who showed much better seizure reduction.

CANCER

CBD usage for cancer treatment has been a big debate over the last few years, as many people claimed that CBD has natural properties that could cure cancer, but could not be used because of legal reasons.

A lot of research has been done in this area. Currently research shows, in human beings, that CBD has only proven to work with some kind of glioma (Brain cancer). CBD helps to shrink the cancerous regions, and make them more prone to further reduction with radiation.

However, a lot of research in animal models is being done, showing really optimistic results in some kinds of common cancer types, such as Breast Cancer. The results show that a combination of the actual treatment with a supplement of CBD in early stages, could stop the tumour’s growth.

ANXIETY AND SUBSTANCE ABUSE

Several studies discuss the possibility of using CBD as a treatment for psychiatric conditions such as anxiety, and alcohol / drug abuse.

The scientific debate has lead researchers to conclude that CBD is an effective treatment to re-teach people with these types of conditions. People with alcohol-use-disorder could benefit directly from properties found in CBD, as it assists with reduction in the amount of alcohol they ingest, consequently improving their liver and brain status.

On the other hand, CDB has only had great performance with anxiety problems in animal models. There is no substantial evidence right now, in human beings, to link it with anxiety reduction.

INSOMNIA

Many of the reviewed studies suggested that CBD could improve the quality of our sleep, decreasing both sleep disturbance and sleep onset latency. Meaning that a deeper and undisturbing sleep can be achieved.

Although it is true that many of those studies showed a positive effect, they had many limitations. Much more research should be done on the topic to have a valid conclusion.

Juan Carlos | Medical Practitioner

PAINKILLERS

Some studies suggest that CBD can work as a pain reliever, as it can mediate inflammation. This would mean that it could be an effective treatment for many different kinds of pain.

 Research remarks its ability to treat:

  • Chronic
  • Neuropathic (involves a malfunction on the nervous system)
  • Refractory pain

These also happen to be the most difficult types of pain to treat conventionally.

It was also found that humans are not likely to develop a tolerance to CBD, which occurs with many other drugs. At the moment, there are no commercialized medications in the market for painkiller purposes. The market for painkillers based on CBD exist, especially when considering inflammatory diseases such as arthritis pain or as some Spinal cord injuries.

SIDE EFFECTS

Human CBD studies for epilepsy and psychiatric disorders reported side effects such as:

  • Drug-to-drug interactions
  • Liver alterations in lab tests
  • Diarrhoea
  • Fatigue
  • Vomiting
  • Decreased appetite
  • Somnolence
At the same time studies suggest that children may be more susceptible to suffering 
CBD-induced side effects.

Meaning that doctors should really balance the risks and benefits of CBD medication before prescribing it. 

Even though it is not a side effect, it should be stated that right now CBD is primarily sold as a supplement and not a medication. Meaning that the FDA does not currently regulate the safety and purity of CBD supplements.

OTHERS

While other there exist cases of disease where CBD has been used for medical treatment, there is not enough substantial data to ensure its effectiveness.

CBD has been used to treat Multiple Sclerosis, reducing the spasticity of the patients. It has also been used to treat schizophrenia, acne and Diabetes Type 1.

Conclusion.

Aside from all the evidence of benefits and side effects shown before, there is still much more research to do. From doses, illnesses and particularly drug-to-drug interactions, all should be deeply studied and tested before being used as medication for human beings.

CBD is not treated as a drug but as a supplement. Meaning that the FDA does not control the 
dosage. It is recommended to talk to a doctor before starting any form of CBD-dependent
treatment.

Even though pharmaceutical companies work slowly to ensure valid results, we can be completely sure that new CBD medication will continue to flood our lives.